Van Lanen, Steven G. : rechercher sur Z-Library

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1

Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196

Funabashi, Masanori, Nonaka, Koichi, Yada, Chieko, Hosobuchi, Masahiko, Masuda, Nobuhisa, Shibata, Tomoyuki, Van Lanen, Steven G

Journal:

The Journal of Antibiotics

Année:

2009

Langue:

english

Fichier:

PDF, 320 KB

english, 2009

2

Structure-Based Gene Targeting Discovery of Sphaerimicin, a Bacterial Translocase I Inhibitor

Funabashi, Masanori, Baba, Satoshi, Takatsu, Toshio, Kizuka, Masaaki, Ohata, Yasuo, Tanaka, Masahiro, Nonaka, Koichi, Spork, Anatol P., Ducho, Christian, Chen, Wei-Chen Leyla, Van Lanen, Steven G.

Journal:

Angewandte Chemie International Edition

Année:

2013

Langue:

english

Fichier:

PDF, 858 KB

english, 2013

3

Nature’s combinatorial biosynthesis and recently engineered production of nucleoside antibiotics inStreptomyces

Chen, Shawn, Kinney, William A., Van Lanen, Steven

Journal:

World Journal of Microbiology and Biotechnology

Année:

2017

Langue:

english

Fichier:

PDF, 903 KB

english, 2017

4

Enzymatic Total Synthesis of Defucogilvocarcin M and Its Implications for Gilvocarcin Biosynthesis

Dr. Pallab Pahari, Prof. Dr. Madan K. Kharel, Dr. Micah D. Shepherd, Prof. Dr. Steven G. van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie International Edition

Année:

2012

Langue:

english

Fichier:

PDF, 358 KB

english, 2012

5

Characterization of a dual specificity aryl acid adenylation enzyme with dual function in nikkomycin biosynthesis

Mary Moon, Steven G. Van Lanen

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 681 KB

english, 2010

6

The Biosynthesis of Liposidomycin-like A-90289 Antibiotics Featuring a New Type of Sulfotransferase

Masanori Funabashi, Satoshi Baba, Koichi Nonaka, Masahiko Hosobuchi, Yoko Fujita, Tomoyuki Shibata, Steven G. Van Lanen

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 392 KB

english, 2010

7

Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin

Ute Galm, Martin H. Hager, Steven G. van Lanen, Jianhua Ju, Jon S. Thorson, Ben Shen

Journal:

Année:

2005

Fichier:

PDF, 8 KB

2005

8

The Neocarzinostatin Biosynthetic Gene Cluster from Streptomyces carzinostaticus ATCC 15944 Involving Two Iterative Type I Polyketide Synthases

Wen Liu, Koichi Nonaka, Liping Nie, Jian Zhang, Steven D. Christenson, Juyun Bae, Steven G. Van Lanen, Emmanuel Zazopoulos, Chris M. Farnet, Catherine F. Yang, Ben Shen

Journal:

Chemistry & Biology

Année:

2005

Langue:

english

Fichier:

PDF, 395 KB

english, 2005

9

Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027

Steven G. Van Lanen, Shuangjun Lin, Geoff P. Horsman, Ben Shen

Journal:

FEMS Microbiology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 306 KB

english, 2009

10

An ATP-independent strategy for amide bond formation in antibiotic biosynthesis

Funabashi, Masanori, Yang, Zhaoyong, Nonaka, Koichi, Hosobuchi, Masahiko, Fujita, Yoko, Shibata, Tomoyuki, Chi, Xiuling, Van Lanen, Steven G

Journal:

Nature Chemical Biology

Année:

2010

Langue:

english

Fichier:

PDF, 468 KB

english, 2010

11

Biosynthesis of Albomycin δ 2 Provides a Template for Assembling Siderophore and Aminoacyl-tRNA Synthetase Inhibitor Conjugates

Zeng, Yu, Kulkarni, Aditya, Yang, Zhaoyong, Patil, Preeti B., Zhou, Wei, Chi, Xiuling, Van Lanen, Steven, Chen, Shawn

Journal:

ACS Chemical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 571 KB

english, 2012

12

Enzymatic Total Synthesis of Defucogilvocarcin M and Its Implications for Gilvocarcin Biosynthesis

Dr. Pallab Pahari, Prof. Dr. Madan K. Kharel, Dr. Micah D. Shepherd, Prof. Dr. Steven G. van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie

Année:

2012

Langue:

english

Fichier:

PDF, 350 KB

english, 2012

13

Zusammenwirken zweier difunktionaler Enzyme bei Aufbau und Verknüpfung von Desoxyzuckern des Antitumor-Antibiotikums Mithramycin

Dr. Guojun Wang, Dr. Pallab Pahari, Dr. Madan K. Kharel, Dr. Jing Chen, Prof. Dr. Haining Zhu, Prof. Dr. Steven G. Van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie

Année:

2012

Langue:

german

Fichier:

PDF, 470 KB

german, 2012

14

Cooperation of Two Bifunctional Enzymes in the Biosynthesis and Attachment of Deoxysugars of the Antitumor Antibiotic Mithramycin

Dr. Guojun Wang, Dr. Pallab Pahari, Dr. Madan K. Kharel, Dr. Jing Chen, Prof. Dr. Haining Zhu, Prof. Dr. Steven G. Van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie International Edition

Année:

2012

Langue:

english

Fichier:

PDF, 672 KB

english, 2012

15

Microbial genomics for the improvement of natural product discovery

Steven G Van Lanen, Ben Shen

Journal:

Current Opinion in Microbiology

Année:

2006

Langue:

english

Fichier:

PDF, 434 KB

english, 2006

16

Progress in combinatorial biosynthesis for drug discovery

Steven G. Van Lanen, Ben Shen

Journal:

Drug Discovery Today: Technologies

Année:

2006

Langue:

english

Fichier:

PDF, 590 KB

english, 2006

17

Biosynthetic Origin and Mechanism of Formation of the Aminoribosyl Moiety of Peptidyl Nucleoside Antibiotics

Chi, Xiuling, Pahari, Pallab, Nonaka, Koichi, Van Lanen, Steven G.

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2011

18

Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l -Threonine:Uridine-5′-Aldehyde Transaldolase

Barnard-Britson, Sandra, Chi, Xiuling, Nonaka, Koichi, Spork, Anatol P., Tibrewal, Nidhi, Goswami, Anwesha, Pahari, Pallab, Ducho, Christian, Rohr, Jurgen, Van Lanen, Steven G.

Journal:

Journal of the American Chemical Society

Année:

2012

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2012

19

Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity

Shepherd, Micah D., Kharel, Madan K., Zhu, Lili L., van Lanen, Steven G., Rohr, Jürgen

Journal:

Organic & Biomolecular Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 259 KB

english, 2010

20

Biosynthesis: A sulfonate relay revealed

Van Lanen, Steven G.

Journal:

Nature Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 245 KB

english, 2013

21

Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin

Galm, Ute, Hager, Martin H., Van Lanen, Steven G., Ju, Jianhua, Thorson, Jon S., Shen, Ben

Journal:

Chemical Reviews

Année:

2005

Langue:

english

Fichier:

PDF, 443 KB

english, 2005

22

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S -Adenosyl- L -Methionine Analogues

Singh, Shanteri, Zhang, Jianjun, Huber, Tyler D., Sunkara, Manjula, Hurley, Katherine, Goff, Randal D., Wang, Guojun, Zhang, Wen, Liu, Chunming, Rohr, Jürgen, Van Lanen, Steven G., Morris, Andrew J.,

Journal:

Angewandte Chemie International Edition

Année:

2014

Langue:

english

Fichier:

PDF, 1002 KB

english, 2014

23

The Role of Tandem Acyl Carrier Protein Domains in Polyunsaturated Fatty Acid Biosynthesis

Jiang, Hui, Zirkle, Ross, Metz, James G., Braun, Lisa, Richter, Leslie, Van Lanen, Steven G., Shen, Ben

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 259 KB

english, 2008

24

Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne Biosynthesis

Van Lanen, Steven G., Oh, Tae-jin, Liu, Wen, Wendt-Pienkowski, Evelyn, Shen, Ben

Journal:

Journal of the American Chemical Society

Année:

2007

Langue:

english

Fichier:

PDF, 372 KB

english, 2007

25

Regiospecific Chlorination of ( S )-β-Tyrosyl- S -Carrier Protein Catalyzed by SgcC3 in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Lin, Shuangjun, Van Lanen, Steven G., Shen, Ben

Journal:

Journal of the American Chemical Society

Année:

2007

Langue:

english

Fichier:

PDF, 181 KB

english, 2007

26

Kinetic Mechanism of the tRNA-Modifying Enzyme S -Adenosylmethionine:tRNA Ribosyltransferase-Isomerase (QueA) †

Van Lanen, Steven G., Iwata-Reuyl, Dirk

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 176 KB

english, 2003

27

Characterization of NcsB2 as a Promiscuous Naphthoic Acid/Coenzyme A Ligase Integral to the Biosynthesis of the Enediyne Antitumor Antibiotic Neocarzinostatin

Cooke, Heather A., Zhang, Jian, Griffin, Meghan A., Nonaka, Koichi, Van Lanen, Steven G., Shen, Ben, Bruner, Steven D.

Journal:

Journal of the American Chemical Society

Année:

2007

Langue:

english

Fichier:

PDF, 97 KB

english, 2007

28

The Bifunctional Glyceryl Transferase/Phosphatase OzmB Belonging to the HAD Superfamily That Diverts 1,3-Bisphosphoglycerate into Polyketide Biosynthesis

Dorrestein, Pieter C., Van Lanen, Steven G., Li, Wenli, Zhao, Chunhua, Deng, Zixin, Shen, Ben, Kelleher, Neil L.

Journal:

Journal of the American Chemical Society

Année:

2006

Langue:

english

Fichier:

PDF, 96 KB

english, 2006

29

Mechanistic Studies of Bacillus subtilis QueF, the Nitrile Oxidoreductase Involved in Queuosine Biosynthesis †

Lee, Bobby W. K., Van Lanen, Steven G., Iwata-Reuyl, Dirk

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 173 KB

english, 2007

30

Biosynthesis of the β-Amino Acid Moiety of the Enediyne Antitumor Antibiotic C-1027 Featuring β-Amino Acyl- S -carrier Protein Intermediates

Van Lanen, Steven G., Dorrestein, Pieter C., Christenson, Steve D., Liu, Wen, Ju, Jianhua, Kelleher, Neil L., Shen, Ben

Journal:

Journal of the American Chemical Society

Année:

2005

Langue:

english

Fichier:

PDF, 106 KB

english, 2005

31

Roles of the Synergistic Reductive O -Methyltransferase GilM and of O -Methyltransferase GilMT in the Gilvocarcin Biosynthetic Pathway

Tibrewal, Nidhi, Downey, Theresa E., Van Lanen, Steven G., Ul Sharif, Ehesan, O’Doherty, George A., Rohr, Jürgen

Journal:

Journal of the American Chemical Society

Année:

2012

Langue:

english

Fichier:

PDF, 647 KB

english, 2012

32

Characterization of the Two-Component, FAD-Dependent Monooxygenase SgcC That Requires Carrier Protein-Tethered Substrates for the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Lin, Shuangjun, Van Lanen, Steven G., Shen, Ben

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 175 KB

english, 2008

33

The Structure of l -Tyrosine 2,3-Aminomutase from the C-1027 Enediyne Antitumor Antibiotic Biosynthetic Pathway †,‡

Christianson, Carl V., Montavon, Timothy J., Van Lanen, Steven G., Shen, Ben, Bruner, Steven D.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2007

34

Enzymatic strategies and biocatalysts for amide bond formation: tricks of the trade outside of the ribosome

Goswami, Anwesha, Van Lanen, Steven G.

Journal:

Molecular BioSystems

Année:

2015

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2015

35

Substrate Specificity of the Adenylation Enzyme SgcC1 Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Van Lanen, Steven G., Lin, Shuangjun, Dorrestein, Pieter C., Kelleher, Neil L., Shen, Ben

Journal:

Journal of Biological Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 852 KB

english, 2006

36

A branch point of Streptomyces sulfur amino acid metabolism controls the production of albomycin

Kulkarni, Aditya, Zeng, Yu, Zhou, Wei, Van Lanen, Steven, Zhang, Weiwen, Chen, Shawn

Journal:

Applied and Environmental Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2015

37

A Biocatalytic Approach to Capuramycin Analogues by Exploiting a Substrate Permissive N-Transacylase CapW

Liu, Xiaodong, Jin, Yuanyuan, Cai, Wenlong, Green, Keith, Goswami, Anwesha, Garneau-Tsodikova, Sylvie, Nonaka, Koichi, Baba, Satashi, Funabashi, Masanori, Yang, Zhaoyong, Van Lanen, Steven

Journal:

Organic & Biomolecular Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2016

38

Biosynthesis of Enediyne Antitumor Antibiotics

Van Lanen, Steven, Shen, Ben

Journal:

Current Topics in Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 623 KB

english, 2008

39

The Role of a Nonribosomal Peptide Synthetase in l -Lysine Lactamization During Capuramycin Biosynthesis

Liu, Xiaodong, Jin, Yuanyuan, Cui, Zheng, Nonaka, Koichi, Baba, Satoshi, Funabashi, Masanori, Yang, Zhaoyong, Van Lanen, Steven G.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 971 KB

english, 2016

40

Functional AdoMet isosteres resistant to classical AdoMet degradation pathways

Huber, Tyler D., Wang, Fengbin, Singh, Shanteri, Johnson, Brooke R., Zhang, Jianjun, Sunkara, Manjula, Van Lanen, Steven G., Morris, Andrew J., Phillips, George N., Thorson, Jon S

Journal:

ACS Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2016

41

Structure-Based Gene Targeting Discovery of Sphaerimicin, a Bacterial Translocase I Inhibitor

Funabashi, Masanori, Baba, Satoshi, Takatsu, Toshio, Kizuka, Masaaki, Ohata, Yasuo, Tanaka, Masahiro, Nonaka, Koichi, Spork, Anatol P., Ducho, Christian, Chen, Wei-Chen Leyla, Van Lanen, Steven G.

Journal:

Angewandte Chemie

Année:

2013

Langue:

english

Fichier:

PDF, 817 KB

english, 2013

42

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S -Adenosyl- L -Methionine Analogues

Singh, Shanteri, Zhang, Jianjun, Huber, Tyler D., Sunkara, Manjula, Hurley, Katherine, Goff, Randal D., Wang, Guojun, Zhang, Wen, Liu, Chunming, Rohr, Jürgen, Van Lanen, Steven G., Morris, Andrew J.,

Journal:

Angewandte Chemie

Année:

2014

Langue:

english

Fichier:

PDF, 978 KB

english, 2014

43

ChemInform Abstract: Enzymatic Strategies and Biocatalysts for Amide Bond Formation: Tricks of the Trade Outside of the Ribosome

Goswami, Anwesha, Van Lanen, Steven G.

Journal:

Année:

2016

Fichier:

PDF, 16 KB

2016

44

Antibacterial and Cytotoxic Actinomycins Y 6 –Y 9 and Zp from Streptomyces sp. Strain Gö-GS12

Cai, Wenlong, Wang, Xiachang, Elshahawi, Sherif I., Ponomareva, Larissa V., Liu, Xiaodong, McErlean, Matthew R., Cui, Zheng, Arlinghaus, Ashley L., Thorson, Jon S., Van Lanen, Steven G.

Journal:

Journal of Natural Products

Année:

2016

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2016

45

Evidence that oxidative dephosphorylation by the nonheme Fe(II), α-ketoglutarate:UMP oxygenase occurs by stereospecific hydroxylation

Goswami, Anwesha, Liu, Xiaodong, Cai, Wenlong, Wyche, Thomas P., Bugni, Tim S., Meurillon, Maïa, Peyrottes, Suzanne, Perigaud, Christian, Nonaka, Koichi, Rohr, Jürgen, Van Lanen, Steven G.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 918 KB

english, 2017

46

Biosynthesis: SAM cycles up for colibactin

Van Lanen, Steven G

Journal:

Nature Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 432 KB

english, 2017

47

Pyridoxal-5′-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, α-amino acid monooxygenase-decarboxylase

Huang, Ying, Liu, Xiaodong, Cui, Zheng, Wiegmann, Daniel, Niro, Giuliana, Ducho, Christian, Song, Yuan, Yang, Zhaoyong, Van Lanen, Steven G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 980 KB

english, 2018

48

Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics

Koppermann, Stefan, Cui, Zheng, Fischer, Patrick D., Wang, Xiachang, Ludwig, Jannine, Thorson, Jon S., Van Lanen, Steven G., Ducho, Christian

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2018

49

Computer-aided drug design of capuramycin analogues as anti-tuberculosis antibiotics by 3D-QSAR and molecular docking

Jin, Yuanyuan, Fan, Shuai, Lv, Guangxin, Meng, Haoyi, Sun, Zhengyang, Jiang, Wei, Van Lanen, Steven G., Yang, Zhaoyong

Journal:

Langue:

english

Fichier:

PDF, 1.91 MB

english

50

Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471

Cui, Zheng, Wang, Xiachang, Koppermann, Stefan, Thorson, Jon S., Ducho, Christian, Van Lanen, Steven G.

Journal:

Journal of Natural Products

Année:

2018

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2018